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A Plasma Air Decontamination System (PADS) is being developed by ORBITEC for trace contaminant control in spacecraft cabin air, based on non-thermal, atmospheric pressure plasma discharges that generate various highly reactive species that can react with and break down trace air contaminants. It uses a simple and modular design, and may be scaled up or down to meet the requirements of different applications. The prototype PADS reactor has successfully demonstrated removal of ammonia and other selected volatile organic carbons from air, including acetone, ethylbenzene, methane, and methylene chloride. It has the potential to replace the existing high-temperature catalytic oxidizers.