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There are many sources of air pollution that can threaten air quality during space missions. The International Space Station (ISS) is an extremely complex platform that depends on a multi-tiered strategy to control the risk of excessive air pollution. During the seven missions surveyed by this report, the ISS atmosphere was in a safe, steady-state condition; however, there were minor loads added as new modules were attached. There was a series of leaks of octafluoropropane, which is not directly toxic to humans, but did cause changes in air purification operations that disrupted the steady state condition. In addition, off-nominal regeneration of metal oxide canisters used during extravehicular activity caused a serious pollution incident.

For over 40 years, NASA has been putting humans safely into space in part by minimizing microbial risks to crew members. Success of the program to minimize such risks has resulted from a combination of engineering and design controls as well as active monitoring of the crew, food, water, hardware, and spacecraft interior. The evolution of engineering and design controls is exemplified by the implementation of HEPA filters for air treatment, antimicrobial surface materials, and the disinfection regimen currently used on board the International Space Station. Data from spaceflight missions confirm the effectiveness of current measures; however, fluctuations in microbial concentrations and trends in contamination events suggest the need for continued diligence in monitoring and evaluation as well as further improvements in engineering systems. The knowledge of microbial controls and monitoring from assessments of past missions will be critical in driving the design of future spacecraft.

As part of its integrated system test bed capability, NASA's Advanced Life Support Program has undertaken the development of a large-scale advanced life support facility capable of supporting long-duration testing of integrated, regenerative biological and physicochemical life support systems. This facility--the Advanced Life Support Human-Rated Test Facility (HRTF) is currently being built at the Johnson Space Center. The HRTF is comprised of a series of interconnected chambers with a sealed internal environment capable of supporting a test crew of four for periods exceeding one year. The life support system will consist of both biological and physicochemical components and will perform air revitalization, water recovery, food production, solid waste processing, thermal management, and integrated command and control functions. Currently, a portion of this multichamber facility has been constructed and is being outfitted with basic utilities and infrastructure.

The subjective aspects of comfort in three different cooling garments, the MACS-Delphi, Russian Orlan, and LCVG were evaluated. Six subjects (4 males and 2 females) were tested in separate sessions in each garment and in one of two environmental chamber conditions: 24°C and 35°C. Subjects followed a staged exercise/rest protocol with different levels of physical exertion at different stages. Thermal comfort and heat perception were assessed by ratings on visual analog scales. Ratings of physical comfort of the garment and also garment flexibility in positions simulating movements during planetary exploration were also obtained. The findings indicated that both overall thermal comfort and head thermal comfort were rated highest in the MACS-Delphi at 24°C. The Orlan was rated lowest on physical comfort and less flexible in different body positions.

Meeting radiation protection requirements during EVA is predominantly an operational issue with some potential considerations for temporary shelter. The issue of spacesuit shielding is mainly guided by the potential of accidental exposure when operational and temporary shelter considerations fail to maintain exposures within operational limits. In this case, very high exposure levels are possible which could result in observable health effects and even be life threatening. Under these assumptions, potential spacesuit radiation exposures have been studied using known historical solar particle events to gain insight on the usefulness of modification of spacesuit design in which the control of skin exposure is a critical design issue and reduction of blood forming organ exposure is desirable.

The 2001 Mars Odyssey spacecraft Martian Radiation Environment Experiment (MARIE) is a solid-state silicon telescope high-energy particle detector designed to measure galactic cosmic radiation (GCR) and solar particle events (SPEs) in the 20 – 500 MeV/nucleon energy range. In this paper we discuss the instrument design and focus on the observations and measurements of SPEs at Mars. These are the first-ever SPE measurements at Mars. The measurements are compared with the geostationary GOES satellite SPE measurements. We also discuss some of the current interplanetary particle propagation and diffusion theories and models. The MARIE SPE measurements are compared with these existing models.

The Self Contained Atmospheric Protective Ensemble (SCAPE) suits, worn at the Kennedy Space Center (KSC) have been updated from the original 1970's design. The suits were renamed Propellant Handlers Ensemble (PHE) but are still commonly referred to as SCAPE. Several modifications to the suit were done over the last 20 years to improve the design for operational use. However, anthropometric changes in the user population over time have not been addressed. The following study addressed anthropometric concerns in the current SCAPE population. It was found that all suits had at least one area in which the recommended upper limit was exceeded by technicians. The most common areas to exceed the upper limit were: waist circumference, chest circumference and upper thigh circumference. Forearm circumference posed the least concern unless using long gauntlet glove which cause the twist lock ring to be located at the forearm rather than the wrist.

Poly (vinyl chloride) (PVC) matrix membranes which incorporate the ionophore nonactin have been evaluated as cation exchange membranes for ammonium ion transport in an electrolytic cell configuration. Interest exists for the development of cation selective membranes for removal of low levels (<200ppm) of ammonium ions commonly found in recycled effluent streams in such diverse applications as expected in a Space Station and commercial fisheries. Ammonium ions are generated as a decomposition product of urea and over time build up in concentration, thus rendering the water unsuitable for human consumption. Nonactin is commonly used in a PVC matrix for ion-selective electrodes.

Biological wastewater processing has been under investigation by AlliedSignal Aerospace and NASA Johnson Space Center (JSC) for future use in space. Testing at JSC in the Hybrid Regenerative Water Recovery System (HRWRS) in preparation for future closed human testing has been performed. Computer models have been developed to aid in the design of a new four-person immobilized cell bioreactor. The design of the reactor and validation of the computer model is presented. In addition, the total organic carbon (TOC) computer model has been expanded to begin investigation of nitrification. This model is being developed to identify the key parameters of the nitrification process, and to improve the design and operating conditions of nitrifying bioreactors. In addition, the model can be used as a design tool to rapidly predict the effects of changes in operational conditions and reactor design, significantly reducing the number and duration of experiments required.

NASA's Advanced Life Support Program has included as part of its long-range planning the development of a large-scale advanced life support facility capable of supporting long-duration testing of integrated, regenerative biological and physicochemical life support systems. As the designated NASA Field Center responsible for integration and testing of advanced life support systems, Johnson Space Center has undertaken the development of such a facility--the Advanced Life Support Human-Rated Test Facility (HRTF). As conceived, the HRTF is an interconnected five-chamber facility with a sealed internal environment capable of supporting a test crew of four for periods exceeding one year. The life support system which sustains the crew consists of both biological and physicochemical components and will perform air revitalization, water recovery, food production, solid waste processing, thermal management, and integrated control and monitoring functions.

The Orion crew module (CM) is being designed to perform survivable land and water landings. There are many issues associated with post-landing crew survival. In general, the most challenging of the realistic Orion landing scenarios from an environmental control standpoint is the off-nominal water landing. Available power and other consumables will be very limited after landing, and it may not be possible to provide full environmental control within the crew cabin for very long after splashdown. Given the bulk and thermal insulation characteristics of the crew-worn pressure suits, landing in a warm tropical ocean area would pose a risk to crew survival from elevated core body temperatures, if for some reason the crewmembers were not able to remove their suits and/or exit the vehicle. This paper summarizes the analyses performed and conclusions reached regarding post-landing crew survival following a water landing, from the standpoint of the crew's core body temperatures.

Vibrational disturbance magnitude and frequency on space-flight missions is often a critical factor regarding mission success. Both materials processing experiments and astronomical investigations have specific microgravity environmental requirements. Recent efforts have been made to quantify the microgravity environment on the Space Shuttle Columbia by measuring gravity levels produced by specific mission events such as Orbiter engine burns, treadmill and ergometer activities, crew sleep periods, rotating chair operations, and body mass measurement operations. However, no measurements have been made of specific, nominal crewmember activities such as translating about the middeck, flight-deck, or in the Spacelab. This report presents pilot-study data of test subject forces induced by intravehicular activities such as push-offs and landings with both hands and feet. Five subjects participated in this investigation.

An ADvanced Automotive Manikin (ADAM) developed at the National Renewable Energy Laboratory (NREL) is used to evaluate NASA’s liquid cooling garments (LCGs) used in advanced spacesuits. The manikin has 120 separate heated/sweating zones and is controlled by a finite-element physiological model of the human thermo-regulatory system. Previous testing showed the thermal sensation and comfort followed expected trends as the LCG inlet fluid temperature was changed. The Phase II test data demonstrates the repeatability of ADAM by retesting the baseline LCG. Skin and core temperature predictions using ADAM in an LCG/arctic suit combination are compared to NASA physiological data to validate the manikin/model. An additional Orlan LCG configuration is assessed using the manikin and compared to the baseline LCG.

We have conducted experiments on 16 lunar soils and 3 lunar volcanic glass samples to study the extraction of oxygen, an important resource for future lunar bases. The samples were chosen to span the range of composition and mineralogy represented in the Apollo collection. Each sample was reduced in flowing hydrogen for 3 hours at 1050°C. The dominant effect was reduction of Fe2+ (as FeO) in minerals and glass to iron metal, with concomitant release of oxygen. Oxygen extraction was strongly correlated with initial Fe2+ abundance but varied among mineral and glass phases. The experimental reduction of lunar soil and glass provides a method for assessing the oxygen production potential for sites on the lunar surface from lunar orbit. Our results show that oxygen yield from lunar soils can be predicted from knowledge of only one parameter, total iron content. This parameter can be measured from orbit by gamma ray spectrometry or multispectral imaging.

Long duration NASA-Mir program missions, and the planned International Space Station missions, have given impetus for NASA to implement an operational program of psychological preparation, monitoring, and support for its crews. For exploration missions measured in years, the importance of psychological issues increases exponentially beyond what is currently done. Psychologists' role should begin during the vehicle design and crew selection phases. Extensive preflight preparation must focus on individual and team adaptation, and leadership. Factors such as lack of resupply options and communication delays will alter in-flight monitoring and support capabilities, and require a more self-sufficient crew. Involvement in postflight recovery will also be necessry to ensure appropriate reintegration to the family and job.

Integrating physicochemical and biological technologies into a regenerative life support system is a complex technical challenge. NASA recognizes that the depth and breadth of the challenge warrants a comprehensive investigation. NASA is implementing several ground-based projects to look at different systems integration issues. The combined efforts of these activities will enable NASA to develop regenerative life support systems for human exploration of the solar system in the 21st century. This paper provides an overview of NASA's overall approach to ground testing of integrated regenerative life support systems.

The incidence of DCS in null gravity appears to be considerably less than predicted by 1-g experiments. In NASA studies in 1-g, 83% of the incidents of DCS occur in the legs. We report first on a study with a crossover design that indicated a considerable reduction in the decompression Doppler bubble grade in the lower extremities in subjects in simulated microgravity (bed rest) as compared to themselves when ambulatory in unit gravity. Second we describe the results of a cardiovascular deconditioning study using a tail-suspended rat model. Since there may be a reduction in bubble production in 0-g, this would reduce the possibility of acquiring neurological DCS, especially by arterial gas embolism. Further, cardiovascular deconditioning appears to reduce the pulmonary artery hypertension (secondary to gas embolization) necessary to effect arterialization of bubbles.

One of the risks associated with long-term space flights is cancer incidence resulting from chronic exposure to space radiation. Assessment of incurred risk from radiation exposure requires quantifying the dose throughout the body. The space radiation exposure received by Space Shuttle astronauts is measured by thermoluminescent dosimeters (TLDs) worn during every mission. These dosimeters measure the absorbed dose to the skin, but the dose to internal organs is required for estimating the cancer risk induced by space radiation. A method to extrapolate these skin dose measurements to realistic organ specific dose estimates, using the Computerized Anatomical Man (CAM) and Computerized Anatomical Female (CAF) models, is discussed in detail. A transport code, which propagates high energy nucleon and charged particles, is combined with the CAM/CAF-generated shielding areal distributions to evaluate the absorbed dose at selected organ sites.

The quantitative analysis of the food system for long-term space missions is a crucial factor for the comparison of different food plans and for the evaluation of the food system as part of the overall mission. Such analysis should include important factors such as nutrition, palatability, diet cycle length, and psychological issues related to food. This paper will give the details of a mathematical model that was developed during the first author's participation as a Summer Faculty Fellow at Johnson Space Center. The model includes nutrition, palatability, diet cycle length, and psychological issues as important components. The model is compatible with the Equivalent System Mass (ESM) metric previously developed as the Advance Life Support (ALS) Research and Technology Metric.