Search Results

Most of the skin injuries caused by traffic accidents, sports, falls, etc. are in the intermediate strain rate range (1-100s-1), and the injuries may occur at different sites, impact velocities, and orientations. To investigate the multifactorial mechanical properties of rat skin at intermediate strain rates, a three-factor, three-level experimental protocol was established using the standard orthogonal table L9(34), which includes site (upper dorsal, lower dorsal, and ventral side), strain rate (1s-1, 10s-1, and 100 s-1), and sampling orientation (0°, 45°, and 90° relative to the spine). Uniaxial tensile tests were performed on rat skin samples according to the protocol to obtain stress-stretch ratio curves. Failure strain energy was selected as the index, and the influence of each factor on these indexes, the differences between levels of each factor, and the influence of errors on the results were quantified by analysis of variance (ANOVA).

Diffuse Axonal Injury (DAI) is the most common type of traumatic brain injury, and it is associated with the linear and rotational accelerations resulting from head impacts, which often occurs in traffic related and sports accidents. To investigate the degree of influence of linear and rotational acceleration on DAI, a two-factor, two-level rat head impact experimental protocol involving linear and rotational acceleration was established using the L4(23) orthogonal table in this paper. Following the protocol, rats head was injured and diffusion tensor imaging (DTI) was performed at 24h post-injury to obtain the whole brain DAI injury, and the fractional anisotropy (FA) value of the corpus callosum was selected as the evaluation indicator. Using analysis of variance, the sum of squared deviations for the evaluation indicators was calculated to determine the degree of influence of linear acceleration and rotational acceleration on DAI. The results show that, 1.