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Finite element analysis is a well-established methodology in structural dynamics. However, optimization and/or probabilistic studies can be prohibitively expensive because they require repeated FE analyses of large models. Various reanalysis methods have been proposed in order to calculate efficiently the dynamic response of a structure after a baseline design has been modified, without recalculating the new response. The parametric reduced-order modeling (PROM) and the combined approximation (CA) methods are two re-analysis methods, which can handle large model parameter changes in a relatively efficient manner. Although both methods are promising by themselves, they can not handle large FE models with large numbers of DOF (e.g. 100,000) with a large number of design parameters (e.g. 50), which are common in practice. In this paper, the advantages and disadvantages of the PROM and CA methods are first discussed in detail.