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A program has been initiated to develop a single set of man/system integration standards, requirements, and guidelines to design hardware and systems with which the space missions crew will interact. This paper describes the background, key issues, and methodology to be used in developing these standards. Included in the methodology is data collection and requirements analysis as well as technical monitoring and review, which includes a government/industry technical advisory group. This paper also briefly describes work performed on the Space Station Human Productivity study.