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Multidisciplinary Design Optimization (MDO) of an automobile body structure is a challenging task as it involves multiple, often conflicting requirements of safety, durability & NVH. Conventionally MDO process requires running large number of design of experiments (DOE) to explore the full design space and to build response surface for optimization. As the safety simulations are highly nonlinear in nature, they typically require significant amount of computational time and resources. Hence the conventional MDO approach is too expensive if too many design variables are simultaneously considered. In this paper, an alternative approach using Equivalent Static Load (ESL) method has been suggested for MDO which is quicker & accurate. The basic idea of the Equivalent Static Load-Method (ESL) is to divide the original nonlinear dynamic optimization problem into an iterative linear optimization and nonlinear analysis process.