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The Spacelab Life Sciences-2 (SLS-2) mission provided scientists with the unique opportunity of obtaining inflight rodent tissue and blood samples during a 14-day mission flown in October, 1993. In order to successfully obtain these samples, Ames Research Center's Space Life Sciences Payloads Office has developed an innovative, modular approach to packaging the instruments used to obtain and preserve the inflight tissue and blood samples associated with the hematology experiments on SLS-2. The design approach organized the multitude of instruments into 12 different 5x6x1 inch kits which were each used to accomplish a particular experiment functional objective on any given day during the mission. The twelve basic kits included blood processing, isotope and erythropoietin injection, body mass measurement, and microscope slides.

An innovative design that meets both Shuttle and Space Station requirements for a user-friendly, volume-efficient, portable glovebox system has been developed at Ames Research Center (ARC). The Standard Interface Glovebox (SIGB) has been designed as a two Middeck locker-sized system that mounts in a Middeck Rack Structure (MRS) or in any rack using the Standard Interface Rack (SIR) rail spacing. The MRS provides structural support for the SIGB during all aspects of the mission and is an interface consistent with NASA's desire for commonality of mechanical interfaces, allowing the SIGB to be flown on essentially any manned space platform. The SIGB provides an enclosed work volume which operates at negative pressure relative to ambient, as well as excellent lighting and ample work volume for anticipated life sciences-related experiment operations inflight.

A multi-discipline, multi-year collaborative spaceflight research program (NASA/Mir Science Program) has been established between the United States and Russia utilizing the capabilities of the Russian Mir Space Station and the NASA space shuttle fleet. As a key research discipline to be carried out onboard Mir, fundamental biology research encompasses three basic objectives: first, to investigate long-term effects of microgravity upon plant and avian physiology and developmental biology; second, to investigate the long-term effects of microgravity upon circadian rhythm patterns of biological systems; and third, to characterize the long-term radiation environment (internal and external) of the Russian Mir space station. The first joint U.S./Russian fundamental biology research on-board Mir is scheduled to begin in March, 1995 with the Mir mission 18 and conclude with the docking of the U.S. shuttle to Mir in June, 1995 during the STS-71, Spacelab/Mir Mission-1 (SLM-1).