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Ames Research Center’s Life Sciences Division has developed and flown an extensive array of spaceflight experiment unique equipment (EUE) during the last decade of the twentieth century. Over this ten year span, the EUE developed at ARC supported a vital gravitational biology flight research program executed on several different platforms, including the Space Shuttle, Spacelab, and Space Station Mir. This paper highlights some of the key EUE elements developed at ARC and flown during the period 1990-1999. Resulting lessons learned will be presented that can be applied to the development of similar equipment for the International Space Station.

Samples of Mars surface material will return to Earth in 2014. Prior to curation and distribution to the scientific community the returned samples will be isolated in a special facility until their biological safety has been assessed following protocols established by NASA’s Planetary Protection Office. The primary requirements for the pre-release handling of the Martian samples include protecting the samples from the Earth and protecting the Earth from the sample. A testbed will be established to support the design of such a facility and to test the planetary protection protocols. One design option that is being compared to the conventional Biological Safety Level 4 facility is a double walled differential pressure chamber with airlocks and automated equipment for analyzing samples and transferring them from one instrument to another.

This study examines the current state of the art in rodent habitats as well as the next generation of rodent habitats currently under development at NASAs Ames Research Center. Space Shuttle missions are currently limited in duration to just over two weeks. In contrast to this, future life science missions aboard the Space Station may last months or even years. This will make resource conservation and utilization critical issues in the development of rodent habitats for extended microgravity missions. Emphasis is placed on defining rodent requirements for extended space flights of up to 90 days, and on improving habitability and extending the useful performance life of rodent habitats.

Remote Tower Sensor Systems are proof-of-concept prototypes being developed by NASA/Ames Research Center (NASA/ARC) with collaboration with the FAA and NOAA. RTSS began with the deployment of an Airport Approach Zone Camera System that includes real-time weather observations at San Francisco International Airport. The goal of this research is to develop, deploy, and demonstrate remotely operated cameras and sensors at several major airport hubs and un-towered airports. RTSS can provide real-time weather observations of airport approach zone. RTSS will integrate and test airport sensor packages that will allow remote access to real-time airport conditions and aircraft status.

This paper compares four potential water treatment systems in the context of their applicability to a Mars transit vehicle mission. The systems selected for evaluation are the International Space Station system, a JSC bioreactor-based system, the vapor phase catalytic ammonia removal system, and the direct osmotic concentration system. All systems are evaluated on the basis of their applicability for use in the context of the Mars Reference Mission. Each system is evaluated on the basis of mass equivalency. The results of this analysis indicate that there is effectively no difference between the International Space Station system and the JSC bioreactor configurations. However, the vapor phase catalytic ammonia removal and the direct osmotic concentration systems offer a significantly lower mass equivalency (approximately 1/7 the ISS or bioreactor systems).

One of the major impediments to human Mars missions is the development of appropriate countermeasures for long term physiological response to the micro-gravity environment. A plethora of countermeasure approaches have been advanced from strictly pharmacological measures to large diameter rotating spacecraft that would simulate a 1-g environment (the latter being the most conservative from a human health perspective). The different approaches have significantly different implications not only on the overall system design of a Mars Mission Vehicle (MMV) but on the necessary earth-orbiting platform that would be required to qualify the particular countermeasure system. It is found that these different design options can be conveniently categorized in terms of the order of magnitude of the rotation diameter required (100's, 10's, 1's, 0 meters). From this, the different mass penalties associated with each category can be generally compared.

The cognitive abilities of some astronauts are affected during spaceflight. We investigated whether a simulated space flight ascent environment, including vibration and 3.8 Gx ascent forces, would result in cognitive deficits detectable by the WinSCAT test battery. Eleven participants were administered the computerized cognitive test battery, a workload rating questionnaire and a subjective state questionnaire before and after a combination of acceleration plus vibration conditions. The acceleration plus vibration exposure resulted in significant self-reports of physical discomfort but did not significantly affect cognitive test battery scores. We discuss ways in which a cognitive assessment tool could be made more sensitive to subtle cognitive changes relevant to astronaut performance.

The study of life in extreme environments provides an important basis from which we can undertake the search for extraterrestrial life. This paper provides a description of a program focused on developing technologies which are necessary to evaluate the potential for the existence of a deep sub-seafloor biosphere.

This paper features a set of advanced technologies for autonomy and intelligence in advanced inspection systems of facility operations. These technologies offer a significant contribution to set a path to establish a system and an operating environment with autonomy and intelligence for inspection, monitoring and safety via gas and ambient sensors, video mining and speech recognition commands on unmanned ground vehicles and other platforms to support operational activities in the Cryogenics Test bed and other facilities and vehicles. These advanced technologies are in current development and progress and their functions and operations require guidance and formulation in conjunction with the development team(s) toward the system architecture.

The least expensive life support for brief human missions is direct supply of all water and oxygen from Earth without any recycling. The currently most advanced human life support system was designed for the International Space Station (ISS) and will use physicochemical systems to recycle water and oxygen. This paper compares physicochemical to direct supply air and water life support systems using Equivalent Mass (EM). EM breakeven dates and EM ratios show that physicochemical systems are more cost effective for longer mission durations.

Pyrolysis processing of solid waste in space will inevitably lead to carbon formation as a primary pyrolysis product. The amount of carbon depends on the composition of the starting materials and the pyrolysis conditions (temperature, heating rate, residence time, pressure). Many paper and plastic materials produce almost no carbon residue upon pyrolysis, while most plant biomass materials or human wastes will yield up to 20-40 weight percent on a dry, as-received basis. In cases where carbon production is significant, it can be stored for later use to produce CO2 for plant growth. Alternatively it can be partly gasified by an oxidizing gas (e.g., CO2, H2O, O2) in order to produce activated carbon. Activated carbons have a unique capability of strongly absorbing a great variety of species, ranging from SO2 and NOx, trace organics, mercury, and other heavy metals.

Life Sciences research on Space Station will utilize rats to study the effects of the microgravity environment on mammalian physiology and to develop countermeasures to those effects for the health and safety of the crew. The animals will produce metabolic water which must be reclaimed to minimize logistics support. The condensate from the Research Animal Holding Facility (RAHF) flown on Spacelab Life Sciences-2 (SLS-2) in October 1993 was used as an analog to determine the type and quantity of constituents which the Space Station (SS) water reclamation system will have to process. The most significant organics present in the condensate were 2-propanol, glycerol, ethylene glycol, 1,2-propanediol, acetic acid, acetone, total proteins, urea and caprolactam while the most significant inorganic was ammonia. Microbial isolates included Xanthomonas, Sphingobacterium, Pseudomonas, Penicillium, Aspergillus and Chrysosporium.

This paper discusses some of the analytical decisions that an investigator must make during the course of a life support system trade study. Equivalent System Mass (ESM) is often applied to evaluate trade study options in the Advanced Life Support (ALS) Program. ESM can be used to identify which of several options that meet all requirements are most likely to have lowest cost. It can also be used to identify which of the many interacting parts of a life support system have the greatest impact and sensitivity to assumptions. This paper summarizes recommendations made in the newly developed ALS ESM Guidelines Document and expands on some of the issues relating to trade studies that involve ESM.

Popular depictions of space exploration as well as government life support research programs have long assumed that future planetary bases would rely on small scale, closed ecological systems with crop plants producing food, water, and oxygen and with bioreactors recycling waste. In actuality, even the most advanced anticipated human life support systems will use physical/ chemical systems to recycle water and oxygen and will depend on food from Earth. This paper compares bioregenerative and physical/chemical life support systems using Equivalent System Mass (ESM), which gauges the relative cost of hardware based on its mass, volume, power, and cooling requirements. Bioregenerative systems are more feasible for longer missions, since they avoid the cost of continually supplying food.

The concept of a general purpose life support system testbed for use in space grew out of considerations arising from the recent consolidation of NASA's Advanced Life Support (ALS) Systems programs. Both the physical-chemical and the biological approaches to regenerative life support will require significant amounts of in-space testing in order to prepare for the final development of systems for human life support. Considerations of the technical requirements and rationales for in-space testing has led to the concept of a common testbed that will allow faster and less expensive long duration tests.

Solid Waste Management (SWM) systems of current and previous space flight missions have employed relatively uncomplicated methods of waste collection, storage and return to Earth. NASA's long-term objectives, however, will likely include human-rated missions that are longer in both duration and distance, with little to no opportunity for re-supply. Such missions will likely exert increased demands upon all sub-systems, particularly the SWM system. In order to provide guidance to SWM Research and Technology Development (R&TD) efforts and overall system development, the establishment of appropriate SWM system requirements is necessary. Because future long duration missions are not yet fully defined, thorough mission-specific requirements have not yet been drafted.

The animal habitat under development for the International Space Station (ISS) provides a unique opportunity for the physiological and biological science community to perform controlled experiments in microgravity on rats and mice. This paper discusses the complexities that arise in developing a new animal habitat to be flown aboard the ISS. Such development is incremental and moves forward by employing the past successes, learning from experienced shortcomings, and utilizing the latest technologies. The standard vivarium cage on the ground can be a very simple construction, however the habitat required for rodents in microgravity on the ISS is extremely complex. This discussion presents an overview of the system requirements and focuses on the unique scientific and engineering considerations in the development of the controlled animal habitat parameters. In addition, the challenges to development, specific science, animal welfare, and engineering issues are covered.

This paper describes engineering rules of thumb for life support system design. One general design rule is that the longer the mission, the more the life support system should use regenerable technologies and recycling. A more specific rule is that, if plants supply more than about half the food, the plants will provide all the oxygen needed by the crew. There are many such design rules that can help in planning the analysis of life support systems or in assessing design concepts. These rules typically describe the results of steady state, “back of the envelope,” trade-off calculations. They are useful in suggesting plausible candidate life support system designs or approaches. Life support system engineers should consider the basic design rules and make quick steady state calculations as a guide before doing detailed design.

In efforts to generate a modeling and simulation system for the environmental control and life support system for a small plant growth chamber, the requirement for a biosynthetic water vapor source was found. The water vapor source was designed to inject a known and controlled rate of water vapor into the laboratory version of NASA Ames Research Center's Salad Machine. The rationale for a water vapor source, the design of the source device, the procedures and results of calibration and the method of integrating and utilizing the device with the Salad Machine are described.

The efficiency and robustness of pilot-automation interaction is a function of the volume of memorized action sequences required to use the automation to perform mission tasks. This paper describes a model of pilot cognition for the evaluation of the cognitive usability of cockpit automation. Five common cockpit automation design errors are discussed with examples.