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With the passage of the Kigali Amendment to the Montreal Protocol, HFC-134a refrigerant will be phased down in all markets worldwide, including those where automotive companies have been slow to embrace HFO-1234yf. Engineers are currently being challenged to design MAC systems using alternate low GWP refrigerants that are allowed by regulations, and are simultaneously cost-effective to manufacture, energy efficient, safe, reliable, affordable for consumers, and also suitable in electrified vehicles.