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Based on the multi-body system, the work research the injury index of the mathematics models of pedestrian, by simulating the motion of the pedestrian impacted by vehicle using MADYMO. Compared with the article published, verify the dependability of this simulated test. Based on the dependability, Carry on sensitivity analysis to design parameter of the automobile. Research on the pedestrian protection by the vehicle by revising the sensitive design parameter. By simulating the pedestrian impacted by the vehicle which installing the hood raise structure, search on the injury index. Compared with the original injury index, we can find that the hood raise structure be propitious to the pedestrian.