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An anatomically detailed rhesus monkey brain FE model was developed to simulate in vivo responses of the brain of sub-human primates subjected to rotational accelerations resulting in diffuse axonal injury (DAI). The material properties used in the monkey model are those in the GHBMC 50th percentile male head model (Global Human Body Model Consortium). The angular loading simulations consisted of coronal, oblique and sagittal plane rotations with the center of rotation in neck to duplicate experimental conditions. Maximum principal strain (MPS) and Cumulative strain damage measure (CSDM) were analyzed for various white matter structures such as the cerebrum subcortical white matter, corpus callosum and brainstem.

Computational human body models, especially detailed finite element models are suitable for investigation of human body kinematic responses and injury mechanism. A real-world lateral vehicle-tree impact accident was reconstructed by using finite element method according to the accident description in the CIREN database. At first, a baseline vehicle FE model was modified and validated according to the NCAP lateral impact test. The interaction between the car and the tree in the accident was simulated using LS-Dyna software. Parameters that affect the simulation results, such as the initial pre-crash speed, impact direction, and the initial impact location on the vehicle, were analyzed. The parameters were determined by matching the simulated vehicle body deformations and kinematics to the accident reports.

Anthropometric test devices (ATDs), such as the Hybrid III crash-test dummy, have been used to simulate lower-extremity responses to military personnel subjected to loading conditions from anti-vehicular (AV) landmine blasts. Numerical simulations [e.g., finite element (FE) analysis] of such high-speed vertical loading on ATD parts require accurate material parameters that are dependent on strain rate. This study presents a combined experimental and computational study to calibrate the rate-dependent properties of three materials on the lower extremities of the Hybrid III dummy. The three materials are heel-pad foam, foot skin, and lower-leg flesh, and each has properties that can affect simulation results of forces and moments transferred to the lower extremities.

Previously, a 10-year-old (YO) pediatric thorax finite element model (FEM) was developed and verified against child chest stiffness data measured from clinical cardiopulmonary resuscitation (CPR). However, the CPR experiments were performed at relatively low speeds, with a maximum loading rate of 250 mm/s. Studies showed that the biomechanical responses of human thorax exhibited rate sensitive characteristics. As such, the studies of dynamic responses of the pediatric thorax FEM are needed. Experimental pediatric cadaver data in frontal pendulum impacts and diagonal belt dynamic loading tests were used for dynamic validation. Thoracic force-deflection curves between test and simulation were compared. Strains predicted by the FEM and the injuries observed in the cadaver tests were also compared for injury assessment and analysis. This study helped to further improve the 10 YO pediatric thorax FEM.

As early as the 1950's, Gurdjian and colleagues (Gurdjian et al., 1955) observed that brain injuries could occur by direct pressure loading without any global head accelerations. This pressure-induced injury mechanism was "forgotten" for some time and is being rekindled due to the many mild traumatic brain injuries attributed to blast overpressure. The aim of the current study was to develop a finite element (FE) model to predict the biomechanical response of rat brain under a shock tube environment. The rat head model, including more than 530,000 hexahedral elements with a typical element size of 100 to 300 microns was developed based on a previous rat brain model for simulating a blunt controlled cortical impact. An FE model, which represents gas flow in a 0.305-m diameter shock tube, was formulated to provide input (incident) blast overpressures to the rat model. It used an Eulerian approach and the predicted pressures were verified with experimental data.

The seatbelt system, originally designed for protecting occupants in frontal crashes, has been reported to be inadequate for preventing occupant head-to-roof contact during rollover crashes. To improve the effectiveness of seatbelt systems in rollovers, in this study, we reviewed previous literature and proposed vertical head excursion corridors during static inversion and dynamic rolling tests for human and Hybrid III dummy. Finite element models of a human and a dummy were integrated with restraint system models and validated against the proposed test corridors. Simulations were then conducted to investigate the effects of varying design factors for a three-point seatbelt on vertical head excursions of the occupant during rollovers. It was found that there were two contributing parts of vertical head excursions during dynamic rolling conditions.

Digital human modeling (DHM) progress worldwide will be much faster and cohesive if the diverse community now developing simulations has a global blueprint for DHM, and is able to work together efficiently. DHM developers and users can save time by building on each other's work. This paper highlights a panel discussion on DHM goals and strategic plans for the next decade to begin formulating the international blueprint. Four subjects are chosen as the starting points: (1) moving DHM into the public safety and internet arenas, (2) role of DHM in computer assisted surgery and automotive safety, (3) DHM in defense applications, and (4) DHM to improve workplace ergonomics.

EuroNCAP and regulations in Europe and Japan evaluate the pedestrian protection performance of cars. The test methods are similar and they all have requirements for the passive protection of the hood area at a pedestrian to car impact speed of 40 km/h. In Europe, a proposal for a second phase of the regulation mandates a brake-assist system along with passive requirements. The system assists the driver in optimizing the braking performance during panic braking, resulting in activation only when the driver brakes sufficiently. In a European study this was estimated to occur in about 50% of pedestrian accidents. A future system for brake assistance will likely include automatic braking, in response to a pre-crash sensor, to avoid or mitigate injuries of vulnerable road users. An important question is whether these systems will provide sufficient protection, or if a parallel, passive pedestrian protection system will be necessary.

The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. The mechanical properties of the bovine PAC under tensile loading have been characterized previously. However, the transverse properties of this structure, such as shear and normal traction which are equally important to understanding the skull/brain interaction under traumatic loading, have not been investigated. These material properties are essential information needed to adequately define the material model of the PAC in a finite element (FE) model of human brain. The purpose of this study was to determine, experimentally, the material properties of the PAC under normal traction loading. PAC specimens were obtained from freshly slaughtered bovine subjects from various locations.

High-speed biplane x-ray and neutral density targets were used to examine brain displacement and deformation during impact. Relative motion, maximum principal strain, maximum shear strain, and intracranial pressure were measured in thirty-five impacts using eight human cadaver head and neck specimens. The effect of a helmet was evaluated. During impact, local brain tissue tends to keep its position and shape with respect to the inertial frame, resulting in relative motion between the brain and skull and deformation of the brain. The local brain motions tend to follow looping patterns. Similar patterns are observed for impact in different planes, with some degree of posterior-anterior and right-left symmetry. Peak coup pressure and pressure rate increase with increasing linear acceleration, but coup pressure pulse duration decreases. Peak average maximum principal strain and maximum shear are on the order of 0.09 for CFC 60 Hz data for these tests.

The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. However, the mechanical properties of the pia-arachnoid complex and its influence on the overall response of the brain have not been well characterized. Consequently, finite element (FE) brain models have tended to oversimplify the response of the pia-arachnoid complex, possibly resulting in a loss of accuracy in the model predictions. The aim of this study was to determine, experimentally, the material properties of the pia-arachnoid complex under quasi-static and dynamic loading conditions. Specimens of the pia-arachnoid complex were obtained from the parietal and temporal regions of freshly slaughtered bovine subjects with the specimen orientation recorded. Single-stroke, uniaxial quasi-static and dynamic tensile experiments were performed at strain-rates of 0.05, 0.5, 5 and 100 s-1 (n = 10 for each strain rate group).

Complete validation of any finite element (FE) model of the human brain is very difficult due to the lack of adequate experimental data. However, more animal brain injury data, especially rat data, obtained under well-defined mechanical loading conditions, are available to advance the understanding of the mechanisms of traumatic brain injury. Unfortunately, internal response of the brain in these experimental studies could not be measured. The aim of this study was to develop a detailed FE model of the rat brain for the prediction of intracranial responses due to different impact scenarios. Model results were used to elucidate possible brain injury mechanisms. An FE model, consisting of more than 250,000 hexahedral elements with a typical element size of 100 to 300 microns, was developed to represent the brain of a rat. The model was first validated locally against peak brain deformation data obtained from nine unique dynamic cortical deformation (vacuum) tests.

Numerical analyses frequently accompany experimental investigations that study injury biomechanics and improvements in automotive safety. Limited by computational speed, earlier mathematical models tended to simplify the system under study so that a set of differential equations could be written and solved. Advances in computing technology and analysis software have enabled the development of many sophisticated models that have the potential to provide a more comprehensive understanding of human impact response, injury mechanisms, and tolerance. In this article, 50 years of publications on numerical modeling published in the Stapp Car Crash Conference Proceedings and Journal were reviewed. These models were based on: (a) author-developed equations and software, (b) public and commercially available programs to solve rigid body dynamic models (such as MVMA2D, CAL3D or ATB, and MADYMO), and (c) finite element models.

Previous studies have shown that both excessive linear and rotational accelerations are the cause of head injuries. Although the head injury criterion has been beneficial as an indicator of head injury risk, it only considers linear acceleration, so there is a need to consider both types of motion in future safety standards. Advanced models of the head/brain complex have recently been developed to gain a better understanding of head injury biomechanics. While these models have been verified against laboratory experimental data, there is a lack of suitable real-world data available for validation. Hence, using two computer models of the head/brain, the objective of the current study was to reconstruct four real-world crashes with known head injury outcomes in a full-vehicle crash laboratory, simulate head/brain responses using kinematics obtained during these reconstructions, and to compare the results predicted by the models against the actual injuries sustained by the occupant.

Although biomechanical studies on the knee-thigh-hip (KTH) complex have been extensive, interactions between the KTH and various vehicular interior design parameters in frontal automotive crashes for newer models have not been reported in the open literature to the best of our knowledge. A 3D finite element (FE) model of a 50th percentile male KTH complex, which includes explicit representations of the iliac wing, acetabulum, pubic rami, sacrum, articular cartilage, femoral head, femoral neck, femoral condyles, patella, and patella tendon, has been developed to simulate injuries such as fracture of the patella, femoral neck, acetabulum, and pubic rami of the KTH complex. Model results compared favorably against regional component test data including a three-point bending test of the femur, axial loading of the isolated knee-patella, axial loading of the KTH complex, axial loading of the femoral head, and lateral loading of the isolated pelvis.

Several three-dimensional (3D) finite element (FE) models of the human body have been developed to elucidate injury mechanisms due to automotive crashes. However, these models are mainly focused on 50th percentile male. As a first step towards a better understanding of injury biomechanics in the small female, a 3D FE model of a 5th percentile female human chest (FEM-5F) has been developed and validated against experimental data obtained from two sets of frontal impact, one set of lateral impact, two sets of oblique impact and a series of ballistic impacts. Two previous FE models, a small female Total HUman Model for Safety (THUMS-AF05) occupant version 1.0ϐ (Kimpara et al., 2002) and the Wayne State University Human Thoracic Model (WSUHTM, Wang 1995 and Shah et al., 2001) were integrated and modified for this model development.

The objective of this work was to evaluate a new tool for assessing brain injury. Many race car drivers have suffered concussion and other brain injuries and are in need of ways of evaluating better head protective systems and equipment. Current assessment guidelines such as HIC may not be adequate for assessing all scenarios. Finite element models of the brain have the potential to provide much better injury prediction for any scenario. At a previous Motorsports conference, results of a MADYMO model of a racing car and driver driven by 3-D accelerations recorded in actual crashes were presented. Model results from nine cases, some with concussion and some not, yielded head accelerations that were used to drive the Wayne State University Head Injury Model (WSUHIM). This model consists of over 310,000 elements and is capable of simulating direct and indirect impacts. It has been extensively validated using published cadaveric test data.

Cerebral blood vessels are an integral part of the brain and may play a role in the response of the brain to impact. The purpose of this study was to quantify the effects of surrogate vessels on the deformation patterns of a physical model of the brain under various impact conditions. Silicone gel and tubing were used as surrogates for brain tissue and blood vessels, respectively. Two aluminum cylinders representing a coronal section of the brain were constructed. One cylinder was filled with silicone gel only, and the other was filled with silicone gel and silicone tubing arranged in the radial direction in the peripheral region. An array of markers was embedded in the gel in both cylinders to facilitate strain calculation via high-speed video analysis. Both cylinders were simultaneously subjected to a combination of linear and angular acceleration using a two-segment pendulum.

Typical automotive related abdominal injuries occur due to contact with the rim of the steering wheel, seatbelt and armrest, however, the rate is less than in other body regions. When solid abdominal organs, such as the liver, kidneys and spleen are involved, the injury severity tends to be higher. Although sled and pendulum impact tests have been conducted using cadavers and animals, the mechanical properties and the tissue level injury tolerance of abdominal solid organs are not well characterized. These data are needed in the development of computer models, the improvement of current anthropometric test devices and the enhancement of our understanding of abdominal injury mechanisms. In this study, a series of experimental tests on solid abdominal organs was conducted using porcine liver, kidney and spleen specimens. Additionally, the injury tolerance of the solid organs was deduced from the experimental data.

Brain tissue architecture consists of a complex network of neurons and vasculature interspersed within a matrix of supporting cells. The role of the relatively suffer blood vessels on the more compliant brain tissues during rapid loading has not been properly investigated. Two 2-D finite element models of the human head were developed. The basic model (Model I) consisted of the skull, dura matter, cerebral spinal fluid (CSF), tentorium, brain tissue and the parasagittal bridging veins. The pia mater was also included but in a simplified form which does not correspond to the convolutions of the brain. In Model II, major branches of the cerebral arteries were added to Model I. Material properties for the brain tissues and vasculature were taken from those reported in the literature. The model was first validated against intracranial pressure and brain/skull relative motion data from cadaveric tests.