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Technical Paper

Development of a Pilot Scale Apparatus for Control of Solid Waste Using Low Temperature Oxidation

2007-07-09
2007-01-3135
In February 2004 NASA released “The Vision for Space Exploration.” The important goals outlined in this document include extending human presence in the solar system culminating in the exploration of Mars. Unprocessed waste poses a biological hazard to crew health and morale. The waste processing methods currently under consideration include incineration, microbial oxidation, pyrolysis and compaction. Although each has advantages, no single method has yet been developed that is safe, recovers valuable resources including oxygen and water, and has low energy and space requirements. Thus, the objective of this project is to develop a low temperature oxidation process to convert waste cleanly and rapidly to carbon dioxide and water. In the Phase I project, TDA Research, Inc. demonstrated the potential of a low temperature oxidation process using ozone. In the current Phase II project, TDA and NASA Ames Research Center are developing a pilot scale low temperature ozone oxidation system.
Technical Paper

Accommodating Rodents During Extended Microgravity Missions

1997-07-01
972306
This study examines the current state of the art in rodent habitats as well as the next generation of rodent habitats currently under development at NASAs Ames Research Center. Space Shuttle missions are currently limited in duration to just over two weeks. In contrast to this, future life science missions aboard the Space Station may last months or even years. This will make resource conservation and utilization critical issues in the development of rodent habitats for extended microgravity missions. Emphasis is placed on defining rodent requirements for extended space flights of up to 90 days, and on improving habitability and extending the useful performance life of rodent habitats.
Technical Paper

Development of the Standard Interface Glovebox (SIGB) for use on Shuttle, MIR, and International Space Station

1997-07-01
972310
An innovative design that meets both Shuttle and Space Station requirements for a user-friendly, volume-efficient, portable glovebox system has been developed at Ames Research Center (ARC). The Standard Interface Glovebox (SIGB) has been designed as a two Middeck locker-sized system that mounts in a Middeck Rack Structure (MRS) or in any rack using the Standard Interface Rack (SIR) rail spacing. The MRS provides structural support for the SIGB during all aspects of the mission and is an interface consistent with NASA's desire for commonality of mechanical interfaces, allowing the SIGB to be flown on essentially any manned space platform. The SIGB provides an enclosed work volume which operates at negative pressure relative to ambient, as well as excellent lighting and ample work volume for anticipated life sciences-related experiment operations inflight.
Technical Paper

Mass Transport in a Spaceflight Plant Growth Chamber

1998-07-13
981553
The Plant Generic BioProcessing Apparatus (PGBA), a plant growth facility developed for commercial space biotechnology research, has flown successfully on 3 spaceflight missions for 4, 10 and 16 days. The environmental control systems of this plant growth chamber (28 liter/0.075 m2) provide atmospheric, thermal, and humidity control, as well as lighting and nutrient supply. Typical performance profiles of water transpiration and dehumidification, carbon dioxide absorption (photosynthesis) and respiration rates in the PGBA unit (on orbit and ground) are presented. Data were collected on single and mixed crops. Design options and considerations for the different sub-systems are compared with those of similar hardware.
Technical Paper

An Evaluation of Potential Mars Transit Vehicle Water Treatment Systems

1998-07-13
981538
This paper compares four potential water treatment systems in the context of their applicability to a Mars transit vehicle mission. The systems selected for evaluation are the International Space Station system, a JSC bioreactor-based system, the vapor phase catalytic ammonia removal system, and the direct osmotic concentration system. All systems are evaluated on the basis of their applicability for use in the context of the Mars Reference Mission. Each system is evaluated on the basis of mass equivalency. The results of this analysis indicate that there is effectively no difference between the International Space Station system and the JSC bioreactor configurations. However, the vapor phase catalytic ammonia removal and the direct osmotic concentration systems offer a significantly lower mass equivalency (approximately 1/7 the ISS or bioreactor systems).
Technical Paper

Space Station Lessons Learned from NASA/Mir Fundamental Biology Research Program

1998-07-13
981606
Ames Research Center's Life Sciences Division was responsible for managing the development of fundamental biology flight experiments during the Phase 1 NASA/Mir Science Program. Beginning with astronaut Norm Thagard's historic March, 1995 Soyuz rendezvous with the Mir station and continuing through Andy Thomas' successful return from Mir onboard STS-91 in June, 1998, the NASA/Mir Science Program has provided scientists with unparalleled long duration research opportunities. In addition, the Phase 1 program has yielded many valuable lessons to program and project management personnel who are managing the development of future International Space Station payload elements. This paper summarizes several of the key space station challenges faced and associated lessons learned by the Ames Research Center Fundamental Biology Research Project.
Technical Paper

Pressure-Sensitive Paint Technology Applied to Low-Speed Automotive Testing

2001-03-05
2001-01-0626
Pressure-sensitive paint (PSP) technology is a technique used to experimentally determine surface pressures on models during wind tunnel tests. The key to this technique is a specially formulated pressure-sensitive paint that responds to, and can be correlated with the local air pressure. Wind tunnel models coated with pressure-sensitive paint are able to yield quantitative pressure data on an entire model surface in the form of light intensity values in recorded images. Quantitative results in terms of pressure coefficients (Cp) are obtained by correlating PSP data with conventional pressure tap data. Only a small number of surface taps are needed to be able to obtain quantitative pressure data with the PSP method. This technique is gaining acceptance so that future automotive wind tunnel tests can be done at reduced cost by eliminating most of the expensive pressure taps from wind tunnel models.
Technical Paper

Space Life Support from the Cellular Perspective

2001-07-09
2001-01-2229
Determining the fundamental role of gravity in vital biological systems in space is one of six science and research areas that provides the philosophical underpinning for why NASA exists. The study of cells, tissues, and microorganisms in a spaceflight environment holds the promise of answering multiple intriguing questions about how gravity affects living systems. To enable these studies, specimens must be maintained in an environment similar to that used in a laboratory. Cell culture studies under normal laboratory conditions involve maintaining a highly specialized environment with the necessary temperature, humidity control, nutrient, and gas exchange conditions. These same cell life support conditions must be provided by the International Space Station (ISS) Cell Culture Unit (CCU) in the unique environment of space. The CCU is a perfusion-based system that must function in microgravity, at unit gravity (1g) on earth, and from 0.1g up to 2g aboard the ISS centrifuge rotor.
Technical Paper

A Testbed for the Mars Returned Sample Handling Facility

2001-07-09
2001-01-2412
Samples of Mars surface material will return to Earth in 2014. Prior to curation and distribution to the scientific community the returned samples will be isolated in a special facility until their biological safety has been assessed following protocols established by NASA’s Planetary Protection Office. The primary requirements for the pre-release handling of the Martian samples include protecting the samples from the Earth and protecting the Earth from the sample. A testbed will be established to support the design of such a facility and to test the planetary protection protocols. One design option that is being compared to the conventional Biological Safety Level 4 facility is a double walled differential pressure chamber with airlocks and automated equipment for analyzing samples and transferring them from one instrument to another.
Technical Paper

Considerations in the Development of Habitats for the Support of Live Rodents on the International Space Station

2001-07-09
2001-01-2228
The animal habitat under development for the International Space Station (ISS) provides a unique opportunity for the physiological and biological science community to perform controlled experiments in microgravity on rats and mice. This paper discusses the complexities that arise in developing a new animal habitat to be flown aboard the ISS. Such development is incremental and moves forward by employing the past successes, learning from experienced shortcomings, and utilizing the latest technologies. The standard vivarium cage on the ground can be a very simple construction, however the habitat required for rodents in microgravity on the ISS is extremely complex. This discussion presents an overview of the system requirements and focuses on the unique scientific and engineering considerations in the development of the controlled animal habitat parameters. In addition, the challenges to development, specific science, animal welfare, and engineering issues are covered.
Technical Paper

The General Purpose Work Station, A Spacious Microgravity Workbench

1992-07-01
921394
The General Purpose Work Station (GPWS) is a laboratory multi-use facility, as demonstrated during the Spacelab Life Sciences 1 (SLS-1) flight. The unit provided particulate containment under varying conditions, served as an effective work space for manipulating live animals, e.g., rats, served as a containment facility for fixatives, and was proposed for use to conduct in-flight maintenance during connector pin repair. The cabinet has a front door large enough to allow installation of a full-size microscope in-flight and is outfitted with a side window to allow delivery of items into the cabinet without exposure to the spacelab atmosphere. Additional support subsystems include inside cabinet mounting, surgical glove fine manipulations capability, and alternating or direct current power supply for experiment equipment, as will be demonstrated during Spacelab J.
Technical Paper

Protein-based Sensors for Environmental Monitoring

2006-07-17
2006-01-2177
Biomolecules exhibit specific binding and high affinity for their ligands. These properties can be exploited to produce sensitive, specific, real-time sensors for analytes that cannot be readily monitored by other methods. Several technologies for environmental monitoring using proteins are currently being developed. We discuss specific challenges to practical application of a family of protein-based sensors derived from bacterial periplasmic binding proteins. We also present recent work to address these challenges.
Technical Paper

Performance Characterization of a Temperature-Swing Adsorption Compressor for Closed-Loop Air Revitalization Based on Integrated Tests with Carbon Dioxide Removal and Reduction Assemblies

2006-07-17
2006-01-2126
CO2 removal, recovery and reduction are essential processes for a closed loop air revitalization system in a crewed spacecraft. Typically, a compressor is required to recover the low pressure CO2 that is being removed from the spacecraft in a swing bed adsorption system. This paper describes integrated tests of a Temperature-Swing Adsorption Compressor (TSAC) with high-fidelity systems for carbon dioxide removal and reduction assemblies (CDRA and Sabatier reactor). It also provides details of the TSAC operation at various CO2 loadings. The TSAC is a solid-state compressor that has the capability to remove CO2 from a low-pressure source, and subsequently store, compress, and deliver it at a higher pressure. TSAC utilizes the principle of temperature-swing adsorption compression and has no rapidly moving parts.
Technical Paper

SMALL-SCALE EXPERIMENTS IN STOVL GROUND EFFECTS

1990-04-01
901060
A series of tests has been completed in which suckdown and fountain forces and pressures were measured on circular plates and twin-tandem-jet generic STOVL (short takeoff and vertical landing) configurations. The tests were conducted using a small-scale hover rig, for jet pressure ratios up to 6 and jet temperatures up to 700°F. The measured suckdown force on a circular plate with a central jet was greater than that found with a commonly used empirical prediction method. The present data showed better agreement with other sets of data. The tests of the generic STOVL configurations were conducted to provide force and pressure data with a parametric variation of parameters so that an empirical prediction method could be developed. The effects of jet pressure ratio and temperature were found to be small. Lift improvement devices were shown to substantially reduce the net suckdown forces. Paper to be presented at SAE Aerospace Meeting, Dayton, Ohio, April 24-27, 1990
Technical Paper

Single Loop for Cell Culture (SLCC) – Development and Spaceflight Qualification of a Perfusion Cell Culture System

2006-07-17
2006-01-2212
Single Loop for Cell Culture (SLCC) consists of individual, self-contained, spaceflight cell culture systems with capabilities for automated growth initiation, feeding, sub-culturing and sampling. The cells are grown and contained within a rigid cell specimen chamber (CSC). Bladder tanks provide flush and media fluid. SLCC uses active perfusion flow to provide nutrients and gas exchange, and to dilute waste products by expelling depleted media fluid into a waste bladder tank. The cells can be grown quiescently, or suspended using magnetically coupled stirrers. This paper describes the functional and safety design features, the operational modes and the spaceflight qualification processes including science validation tests, using yeast as a model organism.
Technical Paper

Carbon Production in Space from Pyrolysis of Solid Waste

2006-07-17
2006-01-2183
Pyrolysis processing of solid waste in space will inevitably lead to carbon formation as a primary pyrolysis product. The amount of carbon depends on the composition of the starting materials and the pyrolysis conditions (temperature, heating rate, residence time, pressure). Many paper and plastic materials produce almost no carbon residue upon pyrolysis, while most plant biomass materials or human wastes will yield up to 20-40 weight percent on a dry, as-received basis. In cases where carbon production is significant, it can be stored for later use to produce CO2 for plant growth. Alternatively it can be partly gasified by an oxidizing gas (e.g., CO2, H2O, O2) in order to produce activated carbon. Activated carbons have a unique capability of strongly absorbing a great variety of species, ranging from SO2 and NOx, trace organics, mercury, and other heavy metals.
Technical Paper

Development of Experiment Kits for Processing Biological Samples In-Flight on SLS-2

1994-06-01
941288
The Spacelab Life Sciences-2 (SLS-2) mission provided scientists with the unique opportunity of obtaining inflight rodent tissue and blood samples during a 14-day mission flown in October, 1993. In order to successfully obtain these samples, Ames Research Center's Space Life Sciences Payloads Office has developed an innovative, modular approach to packaging the instruments used to obtain and preserve the inflight tissue and blood samples associated with the hematology experiments on SLS-2. The design approach organized the multitude of instruments into 12 different 5x6x1 inch kits which were each used to accomplish a particular experiment functional objective on any given day during the mission. The twelve basic kits included blood processing, isotope and erythropoietin injection, body mass measurement, and microscope slides.
Technical Paper

Microgravity Flight - Accommodating Non-Human Primates

1994-06-01
941287
Spacelab Life Sciences-3 (SLS-3) was scheduled to be the first United States man-tended microgravity flight containing Rhesus monkeys. The goal of this flight as in the five untended Russian COSMOS Bion flights and an earlier American Biosatellite flight, was to understand the biomedical and biological effects of a microgravity environment using the non-human primate as human surrogate. The SLS-3/Rhesus Project and COSMOS Primate-BIOS flights all utilized the rhesus monkey, Macaca mulatta. The ultimate objective of all flights with an animal surrogate has been to evaluate and understand biological mechanisms at both the system and cellular level, thus enabling rational effective countermeasures for future long duration human activity under microgravity conditions and enabling technical application to correction of common human physiological problems within earth's gravity, e.g., muscle strength and reloading, osteoporosis, immune deficiency diseases.
Technical Paper

Development of an In-Flight Refill Unit for Replenishing Research Animal Drinking Water

1994-06-01
941283
The Spacelab Life Sciences 2 (SLS-2) mission became NASA's longest duration Shuttle mission, lasting fourteen days, when Columbia landed on November 1, 1993. Located within the Spacelab were a total of 48 laboratory rats which were housed in two Research Animal Holding Facilities (RAHFs) developed by the Space Life Sciences Payloads Office (SLSPO) at Ames Research Center. In order to properly maintain the health and well-being of these important research animals, sufficient quantities of food and water had to be available for the duration of the mission. An Inflight Refill Unit was developed by the SLSPO to replenish the animals' drinking water inflight using the Shuttle potable water system in the middeck galley as the source of additional water. The Inflight Refill Unit consists of two major subsystems, a Fluid Pumping Unit (FPU) and a Collapsible Water Reservoir (CWR).
Technical Paper

Concept for a Life Support System Testbed in Space

1994-06-01
941450
The concept of a general purpose life support system testbed for use in space grew out of considerations arising from the recent consolidation of NASA's Advanced Life Support (ALS) Systems programs. Both the physical-chemical and the biological approaches to regenerative life support will require significant amounts of in-space testing in order to prepare for the final development of systems for human life support. Considerations of the technical requirements and rationales for in-space testing has led to the concept of a common testbed that will allow faster and less expensive long duration tests.
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