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After several decades of human spaceflight, the community of space-faring nations has accumulated a diverse and sometimes harrowing history of toxicological events that have plagued human space endeavors almost from the very beginning. Some lessons have been learned in ground-based test beds and others were discovered the hard way - when human lives were at stake in space. From such lessons one can build a risk-management framework for toxicological events to minimize the probability of a harmful exposure, while recognizing that we cannot predict all possible events. Space toxicologists have learned that relatively harmless compounds can be converted by air revitalization systems into compounds that cause serious harm to the crew.

An EVA simulation with a medical contingency scenario was conducted in 2006 with the NASA Haughton-Mars and EVA Physiology System and Performance Projects, to develop medical contingency management and evacuation techniques for planetary surface exploration. A rescue/evacuation system to allow two rescuer astronauts to evacuate one incapacitated astronaut was evaluated. The rescue system was utilized effectively to extract an injured astronaut up a slope of15-25° and into a surface mobility rover for transport to a simulated habitat for advanced medical care. Further research is recommended to evaluate the effects of reduced gravity and to develop synergies with other surface systems for carrying out the contingency procedures.

Spacecraft radiators reject heat to their surroundings. Radiators can be deployable or mounted on the body of the spacecraft. NASA's Crew Exploration Vehicle is to use body mounted radiators. Coatings play an important role in heat rejection. The coatings provide the radiator surface with the desired optical properties of low solar absorptance and high infrared emittance. These specialized surfaces are applied to the radiator panel in a number of ways, including conventional spraying, plasma spraying, or as an appliqué. Not specifically designed for a weathering environment, little is known about the durability of conventional paints, coatings, and appliqués upon exposure to weathering and subsequent exposure to solar wind and ultraviolet radiation exposure. In addition to maintaining their desired optical properties, the coatings must also continue to adhere to the underlying radiator panel.

As part of preparing for the Crew Exploration Vehicle (CEV), the National Aeronautics and Space Administration (NASA) worked on developing the requirements to manage the fire risk. The new CEV poses unique challenges to current fire protection systems. The size and configuration of the vehicle resembles the Apollo capsule instead of the current Space Shuttle or the International Space Station. The smaller free air volume and fully cold plated avionic bays of the CEV requires a different approach in fire protection than the ones currently utilized. The fire protection approach discussed in this paper incorporates historical lessons learned and fire detection and suppression system design philosophy spanning from Apollo to the International Space Station.

Protecting astronauts from space radiation exposure is an important challenge for mission design and operations for future exploration-class and long-duration missions. Crew members are exposed to sporadic solar particle events (SPEs) as well as to the continuous galactic cosmic radiation (GCR). If sufficient protection is not provided the radiation risk to crew members from SPEs could be significant. To improve exposure risk estimates and radiation protection from SPEs, detailed evaluations of radiation shielding properties are required. A model using a modern CAD tool ProE™, which is the leading engineering design platform at NASA, has been developed for this purpose. For the calculation of radiation exposure at a specific site, the cosine distribution was implemented to replicate the omnidirectional characteristic of the 4π particle flux on a surface.

Smoke transport and detection were modeled numerically in the ISS Destiny module using the NIST, Fire Dynamics Simulator code. The airflows in Destiny were modeled using the existing flow conditions and the module geometry included obstructions that simulate the currently installed hardware on orbit. The smoke source was modeled as a 0.152 by 0.152 m region that emitted smoke particulate ranging from 1.46 to 8.47 mg/s. In the module domain, the smoke source was placed in the center of each Destiny rack location and the model was run to determine the time required for the two smoke detectors to alarm. Overall the detection times were dominated by the circumferential flow, the axial flow from the intermodule ventilation and the smoke source strength.

NASA and the FAA are funding the development of ground-based remote sensing systems specifically designed to detect and quantify the icing environment aloft. The goal of the NASA activity is to develop a relatively low cost stand-alone system that can provide practical icing information to the flight community. The goal of the FAA activity is to develop more advanced systems that can identify supercooled large drop (SLD) as well as general icing conditions and be integrated into the existing weather information infrastructure. Both activities utilize combinations of sensing technologies including radar, radiometry, and lidar, along with Internet-available external information such as numerical weather model output where it is found to be useful. In all cases the measured data of environment parameters will need to be converted into a measure of icing hazard before it will be of value to the flying community.

A fire in spacecraft or habitat supporting NASA's Exploration mission could jeopardize the system, mission, and/or crew. Given adequate measures for fire prevention, the hazard from a fire can be significantly reduced if fire detection is rapid and occurs in the early stages of fire development. The simultaneous detection of both particulate and gaseous products has been proven to rapidly detect fires and accurately distinguish between real fires and nuisance sources. This paper describes the development status of gaseous and particulate sensor elements, integrated sensor systems, and system testing. It is concluded that while development is still necessary, the fundamental approach of smart, miniaturized, multisensor technology has the potential to significantly improve the safety of NASA space exploration systems.

Two separate experimental rigs used in tests on NASA and Zero-G Corporation aircrafts flying low-gravity trajectories, and in the NASA 2.2 Second Drop Tower have been developed to test the functioning of the Flexible Membrane Commode (FMC) concept under reduced gravity conditions. The first rig incorporates the flexible, optically opaque membrane bag and the second rig incorporates a transparent chamber with a funnel assembly for evacuation that approximates the size of the membrane bag. Different waste dispensers have been used including a caulking gun and flexible hose assembly, and an injection syringe. Waste separation mechanisms include a pair of wire cutters, an iris mechanism, as well as discrete slug injection. The experimental work is described in a companion paper. This paper focuses on the obtained results and analysis of the data.

To support NASA's goal to improve aviation safety, the Aircraft Icing Project of the Aviation Safety Program has developed a number of education and training aids for pilots and operators on the hazards of atmospheric icing. A review of aircraft incident and accident investigations has revealed that flight crews have not always understood the effects of ice contamination on their aircraft. To increase this awareness, NASA has partnered with regulatory agencies and pilot trade organizations to assure relevant and practical materials that are focused toward the intended pilot audience. A number of new instructional design approaches and media delivery methods have been introduced to increase the effectiveness of the training materials by enhancing the learning experience, expanding user interactivity and participation, and, hopefully, increasing learner retention rates.

The 2001 Mars Odyssey spacecraft Martian Radiation Environment Experiment (MARIE) is a solid-state silicon telescope high-energy particle detector designed to measure galactic cosmic radiation (GCR) and solar particle events (SPEs) in the 20 – 500 MeV/nucleon energy range. In this paper we discuss the instrument design and focus on the observations and measurements of SPEs at Mars. These are the first-ever SPE measurements at Mars. The measurements are compared with the geostationary GOES satellite SPE measurements. We also discuss some of the current interplanetary particle propagation and diffusion theories and models. The MARIE SPE measurements are compared with these existing models.

A thermal analysis of the compressible carbon dioxide (CO2) flow for the Portable Fire Extinguisher (PFE) system has been performed. A SINDA/FLUINT model has been developed for this analysis. The model includes the PFE tank and the Temporary Sleep Station (TeSS) nozzle, and both have an initial temperature of 72 °F. In order to investigate the thermal effect on the nozzle due to discharging CO2, the PFE TeSS nozzle pipe has been divided into three segments. This model also includes heat transfer predictions for PFE tank inner and outer wall surfaces. The simulation results show that the CO2 discharge rates and component wall temperatures fall within the requirements for the PFE system. The simulation results also indicate that after 50 seconds, the remaining CO2 in the tank may be near the triple point (gas, liquid and solid) state and, therefore, restricts the flow.

The International Space Station Waste Collector Subsystem Risk Mitigation Experiment (ISS WCS RME) was flown as the primary (Shuttle) WCS on Space Shuttle flight STS-104 (ISS-7A) in July 2001, to validate new design enhancements. In general, the WCS is utilized for collecting, storing, and compacting fecal & associated personal hygiene waste, in a zero gravity environment. In addition, the WCS collects and transfers urine to the Shuttle waste storage tank. All functions are executed while controlling odors and providing crew comfort. The ISS WCS previously flew on three Shuttle flights as the Extended Duration Orbiter (EDO) WCS, as it was originally designed to support extended duration Space Shuttle flights up to 30 days in length. Soon after its third flight, the Space Shuttle Program decided to no longer require 30 day extended mission duration capability and provided the EDO WCS to the ISS Program.

Major improvements have recently been completed in the approach to spacecraft shielding analysis. A Computer-Aided Design (CAD)-based system has been developed for determining the shielding provided to any point within or external to the spacecraft. Shielding analysis is performed using a commercially available stand-alone CAD system and a customized ray-tracing subroutine contained within a standard engineering modeling software package. This improved shielding analysis technique has been used in several vehicle design projects such as a Mars transfer habitat, pressurized lunar rover, and the redesigned Space Station. Results of these analyses are provided to demonstrate the applicability and versatility of the system.

From November 2010 until May of 2011, NASA's Icing Remote Sensing System was positioned at Platteville, Colorado between the National Science Foundation's S-Pol radar and Colorado State University's CHILL radar (collectively known as FRONT, or ‘Front Range Observational Network Testbed’). This location was also underneath the flight-path of aircraft arriving and departing from Denver's International Airport, which allowed for comparison to pilot reports of in-flight icing. This work outlines how the NASA Icing Remote Sensing System's derived liquid water content and in-flight icing hazard profiles can be used to provide in-flight icing verification and validation during icing and non-icing scenarios with the purpose of comparing these times to profiles of polarized moment data from the two nearby research radars.

Ice accretions that have formed inside gas turbine engines as a result of flight in clouds of high concentrations of ice crystals in the atmosphere have recently been identified as an aviation safety hazard. NASA's Aviation Safety Program (AvSP) has made plans to conduct research in this area to address the hazard. This paper gives an overview of NASA's engine ice-crystal icing research project plans. Included are the rationale, approach, and details of various aspects of NASA's research.

Procedures for rapid microbiological analysis were performed during simulated surface extra-vehicular activity (EVA) at Meteor Crater, Arizona. The fully suited operator swabbed rock (‘unknown’ sample), spacesuit glove (contamination control) and air (negative control). Each swab sample was analyzed for lipopolysaccharide (LPS) and β-1, 3-glucan within 10 minutes by the handheld LOCAD PTS instrument, scheduled for flight to ISS on space shuttle STS-116. This simulated a rapid and preliminary ‘life detection’ test (with contamination control) that a human could perform on Mars. Eight techniques were also evaluated for their ability to clean and remove LPS and β-1, 3-glucan from five surface materials of the EVA Mobility Unit (EMU). While chemical/mechanical techniques were effective at cleaning smooth surfaces (e.g. RTV silicon), they were less so with porous fabrics (e.g. TMG gauntlet).

Meeting radiation protection requirements during EVA is predominantly an operational issue with some potential considerations for temporary shelter. The issue of spacesuit shielding is mainly guided by the potential of accidental exposure when operational and temporary shelter considerations fail to maintain exposures within operational limits. In this case, very high exposure levels are possible which could result in observable health effects and even be life threatening. Under these assumptions, potential spacesuit radiation exposures have been studied using known historical solar particle events to gain insight on the usefulness of modification of spacesuit design in which the control of skin exposure is a critical design issue and reduction of blood forming organ exposure is desirable.

As NASA is preparing to extend man's reach into space, it is expected that astronauts will be required to spend more and more time exposed to the hazards of performing Extra-Vehicular Activity (EVA). One of these hazards includes the risk of the space suit bladder being penetrated by hypervelocity micrometeoroid and orbital debris (MMOD) particles. Therefore, it has become increasingly important to investigate new ways to improve the protectiveness of the current Extravehicular Mobility Unit (EMU) against MMOD penetration. ILC Dover conducted a NASA funded study into identifying methods of improving the current EMU protection. The first part of this evaluation focused on identifying how to increase the EMU shielding, selecting materials to accomplish this, and testing these materials to determine the best lay-up combinations to integrate into the current thermal micrometeoroid garment (TMG) design.

This ground-based study compared the risk of microbubbles during decompression under simulated space extravehicular activities (EVA) after three days of six-degree head-down bed rest with three days of ambulatory control. Test subjects were exposed to a pressure of 44.8 kPa (6.5 psi), breathed 100% oxygen, and exercised at reduced pressure either in the supine (during experimental) or upright (control) position. Circulating microbubbles were monitored by a precordial Doppler ultrasound device, and were found in 52% (12/23) of control and 26% (6/23) of experimental exposures. Survival analysis using Cox proportional hazards regression showed that there was 0.22 times (95% confidence interval=0.07-0.68) reduction in the risk of high grade microbubbles after bed rest, compared to controls (p=0.004). This finding is of importance in evaluating the risk of DCS during EVA.