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A new three-dimensional human head finite element model, consisting of the scalp, skull, dura, falx, tentorium, pia, CSF, venous sinuses, ventricles, cerebrum (gray and white matter), cerebellum, brain stem and parasagittal bridging veins has been developed and partially validated against experimental data of Nahum et al (1977). A frontal impact and a sagittal plane rotational impact were simulated and impact responses from a homogeneous brain were compared with those of an inhomogeneous brain. Previous two-dimensional simulation results showed that differentiation between the gray and white matter and the inclusion of the ventricles are necessary in brain modeling to match regions of high shear stress to locations of diffuse axonal injury (DAI). The three-dimensional simulation results presented here also showed the necessity of including these anatomical features in brain modeling.

Traumatic brain injury (TBI) continues to be a major health problem, with over 500,000 cases per year with a societal cost of approximately $85 billion in the US. Motor vehicle accidents are the leading cause of such injuries. In many cases of TBI widespread disruption of the axons occurs through a process known as diffuse axonal injury (DAI) or traumatic axonal injury (TAI). In the current study, an in vivo TAI model was developed using spinal nerve roots of adult rats. This model was used to determine functional and structural responses of axons to various strains and displacement rates. Fifty-six L5 dorsal nerve roots were each subjected to a predetermined strain range (<10%, 10-20% and >20%) at a specified displacement rate (0.01 mm/sec and 15 mm/sec) only once. Image analysis was used to determine actual strains on the roots during the pull.

Lower extremity injuries in frontal automotive crashes usually occur with footwell intrusion where both the knee and foot are constrained. In order to identify factors associated with tibial shaft injury, a series of numerical simulations were conducted using a finite element model of the whole human body. These simulations demonstrated that tibial mid-shaft injuries in frontal crashes could be caused by an abrupt change in velocity and a high rate of footwell intrusion.

Numerical analyses of head and neck response during side impact are presented in this paper. A mathematical human model for side impact simulation was developed based on previous studies of other researchers. The effects of muscular activities during severe side impact were analyzed with the use of this model. This study shows that the effect of muscular activities is significant especially if the occupant is prepared to resist the impact. This result suggests that the modeling of muscles is important for the simulation of real accident situation.

Complete validation of any finite element (FE) model of the human brain is very difficult due to the lack of adequate experimental data. However, more animal brain injury data, especially rat data, obtained under well-defined mechanical loading conditions, are available to advance the understanding of the mechanisms of traumatic brain injury. Unfortunately, internal response of the brain in these experimental studies could not be measured. The aim of this study was to develop a detailed FE model of the rat brain for the prediction of intracranial responses due to different impact scenarios. Model results were used to elucidate possible brain injury mechanisms. An FE model, consisting of more than 250,000 hexahedral elements with a typical element size of 100 to 300 microns, was developed to represent the brain of a rat. The model was first validated locally against peak brain deformation data obtained from nine unique dynamic cortical deformation (vacuum) tests.

Ten pairs of thawed fresh-frozen human cadaveric lower arm specimens were subjected to lateral three-point bending. Either the radius or ulna were impacted with a 4.5 kg dropped weight at approximately 3 m/s or tested quasi-statically in a materials testing machine. Fracture occurred primarily near the loading site with an average dynamic peak load of 1370 N and average peak moment of 89 Nm. Differences between the radius and ulna were not significant. Static fracture load and moments were approximately 20% lower. Sectional and mineral properties of each specimen near the fracture sites were measured.

Side impact pendulum tests were conducted on Eurosid I and Biosid to assess the biofidelity of the thorax, abdomen and pelvis, and determine injury tolerance levels. Each body region was impacted at 4.5, 6.7, and 9.4 m/s using test conditions which duplicate cadaver impacts with a 15 cm flat-circular 23.4 kg rigid mass. The cadaver database establishes human response and injury risk assessment in side impact. Both dummies showed better biofidelity when compared to the lowest-speed cadaver response corridor. At higher speeds, peak force was substantially higher. The average peak contact force was 1.56 times greater in Biosid and 2.19 times greater in Eurosid 1 than the average cadaver response. The Eurosid I abdomen had the most dissimilar response and lacks biofidelity. Overall, Biosid has better biofidelity than Eurosid I with an average 21% lower peak load and a closer match to the duration of cadaver impact responses for the three body regions.

The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. However, the mechanical properties of the pia-arachnoid complex and its influence on the overall response of the brain have not been well characterized. Consequently, finite element (FE) brain models have tended to oversimplify the response of the pia-arachnoid complex, possibly resulting in a loss of accuracy in the model predictions. The aim of this study was to determine, experimentally, the material properties of the pia-arachnoid complex under quasi-static and dynamic loading conditions. Specimens of the pia-arachnoid complex were obtained from the parietal and temporal regions of freshly slaughtered bovine subjects with the specimen orientation recorded. Single-stroke, uniaxial quasi-static and dynamic tensile experiments were performed at strain-rates of 0.05, 0.5, 5 and 100 s-1 (n = 10 for each strain rate group).

Relative motion between the brain and skull may explain many types of brain injury such as intracerebral hematomas due to bridging veins rupture [1] and cerebral contusions. However, no experimental methods have been developed to measure the magnitude of this motion. Consequently, relative motion between the brain and skull predicted by analytical tools has never been validated. In this study, radio opaque markers were placed in the skull and neutral density markers were placed in the brain in two vertical columns in the occipitoparietal and temporoparietal regions. A bi-planar, high-speed x-ray system was used to track the motion of these markers. Due to limitations in current technology to record the x-ray image on high-speed video cameras, only low- speed (﹤ 4m/s) impact data were available.

A three-dimensional finite element model of a human neck has been developed in an effort to study the mechanics of cervical spine while subjected to impacts. The neck geometry was obtained from MRI scans of a 50th percentile male volunteer. This model, consisting of the vertebrae from C1 through T1 including the intervertebral discs and posterior elements, was constructed primarily of 8-node brick elements. The vertebrae were modeled using linear elastic-plastic materials, while the intervertebral discs were modeled using linear viscoelastic materials. Sliding interfaces were defined to simulate the motion of synovial facet joints. Anterior and posterior longitudinal ligaments, facet joint capsular ligaments, alar ligaments, transverse ligaments, and anterior and posterior atlanto-occipital membranes were modeled as nonlinear bar elements or as tension-only membrane elements. A previously developed head and brain model was also incorporated.

Previous studies have hypothesized that the shoulder may be used to absorb some impact energy and reduce chest injury due to side impacts. Before this hypothesis can be tested, a good understanding of the injury mechanisms and the kinematics of the shoulder is critical for occupant protection in side impact. However, existing crash dummies and numerical models are not designed to reproduce the kinematics and kinetics of the human shoulder. The purpose of this study was to develop a finite element model of the human shoulder in order to achieve a deeper understanding of the injury mechanisms and the kinematics of the shoulder in side impact. Basic anthropometric data of the human shoulder used to develop the skeletal and muscular portions of this model were taken from commercial data packages. The shoulder model included three bones (the humerus, scapula and clavicle) and major ligaments and muscles around the shoulder.

Injuries to the thorax and abdomen comprise a significant percentage of all occupant injuries in motor vehicle accidents. While the percentage of internal chest injuries is reduced for restrained front-seat occupants in frontal crashes, serious skeletal chest injuries and abdominal injuries can still result from interaction with steering wheels and restraint systems. This paper describes the design and performance of prototype components for the chest, abdomen, spine, and shoulders of the Hybrid III dummy that are under development to improve the capability of the Hybrid III frontal crash dummy with regard to restraint-system interaction and injury-sensing capability.

As early as the 1950's, Gurdjian and colleagues (Gurdjian et al., 1955) observed that brain injuries could occur by direct pressure loading without any global head accelerations. This pressure-induced injury mechanism was "forgotten" for some time and is being rekindled due to the many mild traumatic brain injuries attributed to blast overpressure. The aim of the current study was to develop a finite element (FE) model to predict the biomechanical response of rat brain under a shock tube environment. The rat head model, including more than 530,000 hexahedral elements with a typical element size of 100 to 300 microns was developed based on a previous rat brain model for simulating a blunt controlled cortical impact. An FE model, which represents gas flow in a 0.305-m diameter shock tube, was formulated to provide input (incident) blast overpressures to the rat model. It used an Eulerian approach and the predicted pressures were verified with experimental data.

There are many mechanisms for ankle injury to front seat occupants involved in automotive impacts. This study addresses injuries to the ankle joint involving inversion or eversion, in particular at high rates of loading such as might occur in automotive accidents. Injuries included unilateral malleolar fractures and ligament tears, and talus and calcaneous avulsions. Twenty tests have been performed so far, two of them using Hybrid III lower leg and the rest using cadaveric specimens. The specimens were loaded dynamically on the bottom of the foot via a pneumatic cylinder in either an inversion or eversion direction at fixed dorsiflexion and plantarflexion angles. The applied force and accelerations have been measured as well as all the reaction forces and moments. High-speed film was used to obtain the inversiordeversion angle of the foot relative to the tibia and for following ligament stretch.

In view of the new regulations for diesel engine emissions, EGR is used to reduce the NOx emissions. Diluting the charge with EGR affects the autoignition, combustion as well as the regulated and unregulated emissions of diesel engines, under different operating conditions. This paper presents the results of an investigation on the effect of EGR on the global activation energy and order of the autoignition reactions, premixed and mixing-controlled combustion fractions, the regulated (unburned hydrocarbons, NOx, CO and particulates), aldehydes, CO2 and HC speciation. The experiments were conducted on two different direct injection, four-stroke-cycle, single-cylinder diesel engines over a wide range of operating conditions and EGR ratios.

Hat sections made of steel are frequently encountered in automotive body structural components such as front rails. These components can absorb significant amount of impact energy during collisions thereby protecting occupants of vehicles from severe injury. In the initial phase of vehicle design, it will be prudent to incorporate the sectional details of such a component based on an engineering target such as peak load, mean load, energy absorption, or total crush, or a combination of these parameters. Such a goal can be accomplished if efficient and reliable data-based models are available for predicting the performance of a section of given geometry as alternatives to time-consuming and detailed engineering analysis typically based on the explicit finite element method.

Commotio Cordis (CC) is the second leading cause of mortality in youth sports. Impacts occurring directly over the left ventricle (LV) during a vulnerable period of the cardiac cycle can cause ventricular fibrillation (VF), which results in CC. In order to better understand the pathophysiology of CC, and develop a mechanical model for CC, appropriate injury criteria need to be developed. This effort consisted of impacts to seventeen juvenile porcine specimens (mass 21-45 kg). Impacts were delivered over the cardiac silhouette during the venerable period of the cardiac cycle. Four impact speeds were used: 13.4, 17.9, 22.4, and 26.8 m/s. The impactor was a lacrosse ball on an aluminum shaft instrumented with an accelerometer (mass 188 g - 215 g). The impacts were recorded using high-speed video. LV pressure was measured with a catheter. Univariate binary logistic regression analyses were performed to evaluate the predictive ability of ten injury criteria.

Previously, a 10-year-old (YO) pediatric thorax finite element model (FEM) was developed and verified against child chest stiffness data measured from clinical cardiopulmonary resuscitation (CPR). However, the CPR experiments were performed at relatively low speeds, with a maximum loading rate of 250 mm/s. Studies showed that the biomechanical responses of human thorax exhibited rate sensitive characteristics. As such, the studies of dynamic responses of the pediatric thorax FEM are needed. Experimental pediatric cadaver data in frontal pendulum impacts and diagonal belt dynamic loading tests were used for dynamic validation. Thoracic force-deflection curves between test and simulation were compared. Strains predicted by the FEM and the injuries observed in the cadaver tests were also compared for injury assessment and analysis. This study helped to further improve the 10 YO pediatric thorax FEM.

The mechanisms of knee fracture were studied experimentally using cadaveric knees and analytically by computer simulation. Ten 90 degree flexed knees were impacted frontally by a 20 kg pendulum with a rigid surface, a 450 psi (3.103 MPa) crush strength and a 100 psi (0.689 MPa) crush strength aluminum honeycomb padding and a 50 psi (0.345 MPa) crush strength paper honeycomb padding at a velocity of about five m/s. During rigid surface impact, a patella fracture and a split condylar fracture were observed. The split condylar fracture was generated by the patella pushing the condyles apart, based on a finite element model using the maximum principal stress as the injury criterion. In the case of the 450 psi aluminum honeycomb padding, the split condylar fracture still occurred, but no patella fractures were observed because the honeycomb provided a more uniform distribution of patella load. No bony fractures in the knee area occurred for impacts with a 50 psi paper honeycomb padding.

A 3-D finite element human head model has been developed to study the dynamic response of the human head to direct impact by a rigid impactor. The model simulated closely the main anatomical features of an average adult head. It included the scalp, a three-layered skull, cerebral spinal fluid (CSF), dura mater, falx cerebri, and brain. The layered skull, cerebral spinal fluid, and brain were modeled as brick elements with one-point integration. The scalp, dura mater, and falx cerebri were treated as membrane elements. To simulate the strain rate dependent characteristics of the soft tissues, the brain and the scalp were considered as viscoelastic materials. The other tissues of the head were assumed to be elastic. The model contains 6080 nodes, 5456 brick elements, and 1895 shell elements. To validate the head model, it was impacted frontally by a cylinder to simulate the cadaveric tests performed by Nahum et. al. (8).